Goji berries (Lycium barbarum) are the new ‘superfood’ so we are guessing that you are very health conscious and growing them for their nutritious berries. They also make excellent windbreaks and hedges, particularly in coastal areas. They can be planted in any well drained soil in full sun, and once established, they are fairly simple to grow.
Spring is the time to prune them. Wait until the buds begin to break, as it will be easier to see where any stems have died back over winter. Goji Berries only need light pruning, removing dead and damaged wood and reducing the stems to the space available. However if your shrubs are well established and have outgrown their space then they will tolerate harder pruning.
With regards to lifting the plants when they are fruiting, we are assuming that you are growing them in containers. It shouldn’t be necessary to lift them. When the plants have berries on them the best way to protect your crop is by covering them with a protection net to stop birds from ‘harvesting’ your berries before you get to them. You can pick one up at this link: Crop Protection Net.